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- A kinetic model predicts SpCas9 activity, improves off-target classification, and reveals the physical basis of targeting fidelity
A kinetic model predicts SpCas9 activity, improves off-target classification, and reveals the physical basis of targeting fidelity
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Prediction of the sequence-specific cleavage activity of Cas9 variants
CRISPR/Cas9 On- and Off-Target Activity Using Correlative Force and Fluorescence Single-Molecule Microscopy
Improving the on-target activity of high-fidelity Cas9 editors by combining rational design and random mutagenesis
Improving the on-target activity of high-fidelity Cas9 editors by combining rational design and random mutagenesis
Improving the on-target activity of high-fidelity Cas9 editors by combining rational design and random mutagenesis
PDF) A kinetic model predicts SpCas9 activity, improves off-target classification, and reveals the physical basis of targeting fidelity
Human genetic variation alters CRISPR-Cas9 on- and off-targeting specificity at therapeutically implicated loci
A kinetic model predicts SpCas9 activity, improves off-target classification, and reveals the physical basis of targeting fidelity
Prediction of the sequence-specific cleavage activity of Cas9 variants
A deep learning-based model DeepSpCas9 to predict SpCas9 activity
